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[ccp4bb] Postdoctoral position, microRNA biogenesis, Harvard Medical School

- Protein crystallography

Main steps:

   - Protein purification
   - Crystallisation


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   - X-ray detectors

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CCP4bb <-- 2012 <-- March 2012 <-- 07 March 2012
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Subject: Zero occupancy and bad geometry
From: Joel Tyndall joel {- dot -} tyndall {- at -} OTAGO {- dot -} AC {- dot -} NZ
Date: 2012-03-07
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Subject: Re: qualification to serve as the co-author for the protein 3D structure stored in RCSB
From: Eleanor Dodson eleanor {- dot -} dodson {- at -} YORK {- dot -} AC {- dot -} UK
Date: 2012-03-07

Subject: Postdoctoral position, microRNA biogenesis, Harvard Medical School
From: Piotrek Sliz sliz {- at -} HKL {- dot -} HMS {- dot -} HARVARD {- dot -} EDU
Date: 2012-03-07

*Department: Biological Chemistry and Molecular Pharmacology
Location: Longwood Ave., Boston, MA
URL: http://hkl.hms.harvard.edu
Start Date: immediate/negotiable
Description: Our laboratory at Harvard Medical School has an immediate
opening for an protein/RNA crystallographer. Our group recently determined
high resolution X-ray structures of Lin28 with various members of let-7
microRNAs (Nam et al., Cell 2011), a system that has been implicated in
control of cell differentiation, cancer, and cell stemness. Projects are
available in our laboratory to build up on those recent results. As a
member of our group you will utilize a variety of structural biology
techniques, including X-ray Crystallography, SAXS, molecular dynamics and
NMR (in collaboration with Prof. James Chou). You might also collaborate
with members of Children’s Hospital Stem Cell Institute to perform
complementary biological experiments.

Candidates must hold PhD in biochemistry or related fields. Strong
background in molecular biology, biochemistry, large-scale protein
expression and purification of proteins and nucleic acids is desired.

Please submit: To apply, please send a single PDF file that incorporates CV
including contact information of 3 references and list of your experimental

Person to contact: Dr. Piotrek Sliz
Surface mail address: Harvard Medical School. Department of Biological
Chemistry and Molecular Pharmacology. Center for Molecular and Cellular
Dynamics. 250 Longwood Ave., Rm SGM-130, Boston, MA, 02115.
Email address: apply@hkl.hms.harvard.edu*


Piotrek Sliz
Assistant Professor in Pediatrics
Lecturer on BCMP

Harvard Medical School
Center for Molecular and Cellular Dynamics
Voice: (617) 299-1455

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