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Re: [ccp4bb] Domain swapping..... and unswapping. |
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CCP4bb navigationCCP4bb <-- 2007 <-- October 2007 <-- 05 October 2007Subject: Re: Domain swapping..... and unswapping. From: Myron Smith M {- dot -} Smith {- at -} ASTEX-THERAPEUTICS {- dot -} COM Date: 2007-10-05 If you check PDB ID 1K50 you would see that the asymmetric unit contains two monomers and a domain swapped dimmer. The reference if you want to read the paper is: O`Neill, J.W., Kim, D.E., Johnsen, K., Baker, D., Zhang, K.Y. Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus. Structure v9 pp. 1017-1027, 2001 Regards Myron -----Original Message----- From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Miriam-Rose Ash Sent: Friday, October 05, 2007 3:41 PM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Domain swapping..... and unswapping. Hey all, Sorry for the off-topic post, but I'm just wondering if anyone has heard of any examples in which a single crystal contained both the domain-swapped and unswapped forms of a protein? Thanks! Miriam Disclaimer This communication is confidential and may contain privileged information intended solely for the named addressee(s). It may not be used or disclosed except for the purpose for which it has been sent. If you are not the intended recipient you must not review, use, disclose, copy, distribute or take any action in reliance upon it. If you have received this communication in error, please notify Astex Therapeutics Ltd by emailing M.Smith@astex-therapeutics.com and destroy all copies of the message and any attached documents. Astex Therapeutics Ltd monitors, controls and protects all its messaging traffic in compliance with its corporate email policy. The Company accepts no liability or responsibility for any onward transmission or use of emails and attachments having left the Astex Therapeutics domain. Unless expressly stated, opinions in this message are those of the individual sender and not of Astex Therapeutics Ltd. The recipient should check this email and any attachments for the presence of computer viruses. Astex Therapeutics Ltd accepts no liability for damage caused by any virus transmitted by this email. E-mail is susceptible to data corruption, interception, unauthorized amendment, and tampering, Astex Therapeutics Ltd only send and receive e-mails on the basis that the Company is not liable for any such alteration or any consequences thereof. Astex Therapeutics Ltd., Registered in England at 436 Cambridge Science Park, Cambridge CB4 0QA under number 3751674 CCP4bb navigationCCP4bb <-- 2007 <-- October 2007 <-- 05 October 2007 |
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