[ccp4bb] antibody crystallization

Protein crystallography Programs for crystallography X-ray detectors
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Protein Peptide

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CCP4bb <-- 2008 <-- January 2008 <-- 20 January 2008

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From: James Stroud jstroud {- at -} MBI {- dot -} UCLA {- dot -} EDU
Date: 2008-01-20

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Subject: Re: difference between I over sigma I and I over sd
From: "Winter, G (Graeme)" g {- dot -} winter {- at -} DL {- dot -} AC {- dot -} UK
Date: 2008-01-21

Subject: antibody crystallization
From: William Scott wgscott {- at -} CHEMISTRY {- dot -} UCSC {- dot -} EDU
Date: 2008-01-20

Hi folks:

A colleague has an antibody they would like a crystal structure of,
bound to a peptide. Currently it is a whole antibody. From my
superficial search of the literature, it looks like everyone uses Fab
fragments in such cases. Is this true, and is it stupid to try the
whole thing? If anyone would be kind enough to point me to a good
methodological overview for crystallizing these things in the
literature, I would be exceptionally grateful.

Many thanks.

Bill

William G. Scott

Contact info:
http://chemistry.ucsc.edu/~wgscott/

CCP4bb navigation

CCP4bb <-- 2008 <-- January 2008 <-- 20 January 2008

Previous message:
Subject: Re: microsoft 3-button wheel mouse with OS X 10.5
From: James Stroud jstroud {- at -} MBI {- dot -} UCLA {- dot -} EDU
Date: 2008-01-20

Next message:
Subject: Re: difference between I over sigma I and I over sd
From: "Winter, G (Graeme)" g {- dot -} winter {- at -} DL {- dot -} AC {- dot -} UK
Date: 2008-01-21