Re: [ccp4bb] salt sensitive complex

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CCP4bb <-- 2008 <-- January 2008 <-- 23 January 2008

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Subject: Re: Why there are difference density when occupancy is 1.00
From: James Irving irving {- dot -} james {- at -} GMAIL {- dot -} COM
Date: 2008-01-22

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Subject: Re: Characterization of common salt crystal forms?
From: CCP4 ccp4hnaalas {- at -} GMAIL {- dot -} COM
Date: 2008-01-23

Subject: Re: salt sensitive complex
From: CCP4 ccp4hnaalas {- at -} GMAIL {- dot -} COM
Date: 2008-01-23

Dear Jerry,

> Are there some better ways that I can validate the binding affinity?

I think it is possible to calculate the interacting energies by
APBS... once you have the complex structure this is! Would be
interesting to compare the values of the constants you get from ITC
and SPR with the one of the more "theoretical" model with APBS...

HTH

Kind regards.

Leo
------------------------------------------------------------
Chavas Leonard, Ph.D.
Research Associate
------------------------------------------------------------
Faculty of Life Sciences
The University of Manchester
The Michael Smith Building
Oxford Road
Manchester Lancashire
M13 9PT
------------------------------------------------------------
Tel: +44(0)161-275-1586
e-mail: Leonard.Chavas@manchester.ac.uk

CCP4bb navigation

CCP4bb <-- 2008 <-- January 2008 <-- 23 January 2008

Previous message:
Subject: Re: Why there are difference density when occupancy is 1.00
From: James Irving irving {- dot -} james {- at -} GMAIL {- dot -} COM
Date: 2008-01-22

Next message:
Subject: Re: Characterization of common salt crystal forms?
From: CCP4 ccp4hnaalas {- at -} GMAIL {- dot -} COM
Date: 2008-01-23