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Re: [ccp4bb] References for ligand flipping
 

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CCP4bb <-- 2008 <-- February 2008 <-- 18 February 2008
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Subject: Re: References for ligand flipping
From: Kendall Nettles knettles {- at -} SCRIPPS {- dot -} EDU
Date: 2008-02-18
Jon, I have not had any replies. I did hear a talk at an American Chemical
Society meeting on a ligand flipping between the two estrogen receptor
subtypes, but it hasnšt been published from what I can tell. Herešs a link
to the abstract.

membership.acs.org/C/COMP/pastprograms/Fall06abstracts.pdf

Kendall


On 2/18/08 8:38 PM, "Read, Jon" wrote:

> Hi Kendall,
> did you get any replies about this as I would be interested in hearing about
> these. I have seen some talks of kinases which mention this but can't recall
> the targets.
>>
>> -----Original Message-----
>> From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK]On Behalf Of Kendall
>> Nettles
>> Sent: Saturday, February 09, 2008 11:04 AM
>> To: CCP4BB@JISCMAIL.AC.UK
>> Subject: [ccp4bb] References for ligand flipping
>>
>>
>>
>> Hi,
>> Thanks to everyone for suggestions on making disulfides. I do have another
>> question.
>>
>> Can anyone suggest some references for structures showing that a small
>> molecule ligand binds differently in closely related proteins?
>>
>>
>> Thanks,
>> Kendall
>> --
>> Kendall W. Nettles, PhD
>> Assistant Professor
>> Department of Cancer Biology
>> The Scripps Research Institute
>> 5353 Parkside Dr.
>> Jupiter Fl 33458
>>
>





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