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Re: [ccp4bb] Tough Low-Res MR |
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CCP4bb navigationCCP4bb <-- 2008 <-- February 2008 <-- 26 February 2008Subject: Re: Tough Low-Res MR From: James Stroud jstroud {- at -} MBI {- dot -} UCLA {- dot -} EDU Date: 2008-02-26 Thank you for suggesting phaser. It is king. The problem proved not to be trivial but now appears to be solved with great help from phaser. Time to celebrate. James > On Thu, Feb 21, 2008 at 11:48 AM, James Stroud > >> Hello All, >> >> I have a tough ~3.5 Å (pushing it) MR problem where I have a >> solution >> of sorts, but because I'm working with a heterodimer of two closely >> related subunits (with two such heterodimers in the ASU) I have a >> 2**2 >> possibilities for the arrangement of these subunits in the ASU. Each >> subunit is composed of two more-or-less independent domains. >> Basically >> I'm looking for the best possible software to disambiguate this >> problem. I usually use CNS for these problems, but I think I may >> have >> exhausted its capabilities. I've heard that there have been some >> advances in MR in recent years, but I haven't kept up with all of >> the >> software. Does anyone have suggestions for packages to try? CCP4bb navigationCCP4bb <-- 2008 <-- February 2008 <-- 26 February 2008 |
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