[ccp4bb] Off topic - Activators developed using SBDD

Protein crystallography Programs for crystallography X-ray detectors
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From: Catherine Regni regnicat {- at -} YAHOO {- dot -} COM
Date: 2008-02-26

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Subject: Off topic - Activators developed using SBDD
From: Sridhar Prasad SridharP {- at -} MBASIS {- dot -} COM
Date: 2008-02-26

This is an off topic question - relevant to SBDD community.

Could someone please help me in finding references or point to
successful examples of small molecules that are activators of enzymes
developed using Structure Based approach and have become drug
candidates.

We all are aware of many successful stories of small molecule
inhibitors that are now marketed drugs discovered by SBDD approach.

Thanks,

Sridhar

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CCP4bb <-- 2008 <-- February 2008 <-- 26 February 2008

Previous message:
Subject: modified amino acid connection to protein again
From: Catherine Regni regnicat {- at -} YAHOO {- dot -} COM
Date: 2008-02-26