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Re: [ccp4bb] multiple sequence alignment from multiple pairwise structural alignments |
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CCP4bb navigationCCP4bb <-- 2008 <-- March 2008 <-- 05 March 2008Subject: Re: multiple sequence alignment from multiple pairwise structural alignments From: Juergen Bosch jbosch {- at -} U {- dot -} WASHINGTON {- dot -} EDU Date: 2008-03-05 http://www.charite.de/bioinf/strap/ It convinced me. Maybe that should also be included in the CCP4wiki a collection of what program do I use when I want to make X Y or Z Juergen Ashley Buckle wrote: > I can recommend MUSTANG: http://p2p.cs.mu.oz.au/mustang/ > Web server version is http://p2p.cs.mu.oz.au/mustang/php/ > paper is here: > http://www.ncbi.nlm.nih.gov/pubmed/16736488?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum > > Ashley > > On 05/03/2008, at 6:13 AM, Stephen Graham wrote: > >> Hi all, >> >> I would like to generate a structure-based multiple sequence alignment >> using 4 structures. I have already generated pairwise alignments for >> each 'pair' of structures (6 alignments in all). Is there a program >> out there that can take a number of aligned structures (or even just a >> number of pairwise sequence alignments) and calculate the 'best' >> multiple sequence alignment? Please note that there is absolutely no >> sequence conservation between these structures, making standard >> sequence-based alignment tools pretty useless. >> >> Thanks, >> >> Stephen >> >> -- >> Dr Stephen Graham >> Nuffield Medical Fellow >> Division of Structural Biology >> Wellcome Trust Centre for Human Genetics >> Roosevelt Drive >> Oxford OX3 7BN >> United Kingdom >> Phone: +44 1865 287 549 > > > > > Ashley Buckle Ph.D > NHMRC Senior Research Fellow > The Department of Biochemistry and Molecular Biology > School of Biomedical Sciences, Faculty of Medicine & > Victorian Bioinformatics Consortium (VBC) > Monash University, Clayton, Vic 3800 > Australia > > http://www.med.monash.edu.au/biochem/staff/abuckle.html > iChat/AIM: blindcaptaincat > skype: ashley.buckle > Tel: (613) 9902 0269 (office) > Tel: (613) 9905 1653 (lab) > > Fax : (613) 9905 4699 > > > -- Jürgen Bosch University of Washington Dept. of Biochemistry, K-426 1705 NE Pacific Street Seattle, WA 98195 Box 357742 Phone: +1-206-616-4510 FAX: +1-206-685-7002 Web: http://faculty.washington.edu/jbosch CCP4bb navigationCCP4bb <-- 2008 <-- March 2008 <-- 05 March 2008 |
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