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Re: [ccp4bb] MolRep of coiled coils

 

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CCP4bb <-- 2008 <-- March 2008 <-- 28 March 2008
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Subject: Re: MolRep of coiled coils
From: Thomas Edwards T {- dot -} A {- dot -} Edwards {- at -} LEEDS {- dot -} AC {- dot -} UK
Date: 2008-03-28
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Subject: Model ensemble for x-ray crystallography
From: Lucas Bleicher lbleicher {- at -} YAHOO {- dot -} COM
Date: 2008-03-28


Subject: Re: MolRep of coiled coils
From: M T michelthe {- at -} GMAIL {- dot -} COM
Date: 2008-03-28

My short experience with coiled-coil is that molecular replacement can
be difficult for "classical software" (due to the very anysotropic
shape of the protein).
In our case (a short parallel dimeric coiled-coil), molecular
replacement trials using AMoRe or MOLREP were unsuccessful. We solved
the structure using EPMR (evolutionary search molecular replacement
software).
http://www.msg.ucsf.edu/local/programs/epmr/epmr.html

Michel.

CCP4bb navigation

CCP4bb <-- 2008 <-- March 2008 <-- 28 March 2008
Previous message:
Subject: Re: MolRep of coiled coils
From: Thomas Edwards T {- dot -} A {- dot -} Edwards {- at -} LEEDS {- dot -} AC {- dot -} UK
Date: 2008-03-28
Next message:
Subject: Model ensemble for x-ray crystallography
From: Lucas Bleicher lbleicher {- at -} YAHOO {- dot -} COM
Date: 2008-03-28



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